Theses/Dissertations from 2012
DISSECTING KEY DETERMINANTS FOR CALCIUM AND CALMODULIN REGULATION OF GAP JUNCTION AND VIRAL PROTEIN, Yanyi Chen
STRUCTURE AND FUNCTION STUDIES OF SELENIUM SUBSTITUTED NUCLEIC ACIDS, WEN ZHANG
Theses/Dissertations from 2011
Novel Near-Infrared Cyanine Dyes for Fluorescence Imaging in Biological Systems, Nilmi T. Fernando
On the Biochemistry, Mechanism and Physiological Role of Fungal Nitronate Monooxygenase, Kevin Francis
Nucleic Acid Substrates: Investigation of Structural and Dynamic Features that Influence Enzyme Activity, Christopher N. Johnson
Defining a Molecular Mechanism for Lead Toxicity via Calcium-Binding Proteins, Michael Kirberger
Targeted Molecular MR Imaging of HER2 and EGFR Using De Novo Designed Protein Contrast Agents, Jingjuan Qiao
Protein-Nucleic Acid Interactions in Nuclease and Polymerases, abdur rob
Development of Inhibitors and Assay Methods for Histone Acetyltransferases, Jiang Wu
Mechanistic Studies of Two Selected Flavin-Dependent Enzymes: Choline Oxidase and D-Arginine Dehydrogenase, Hongling Yuan
Theses/Dissertations from 2010
Synthesis of Fused Heterocyclic Diamidines for the Treatment of Human African Trypanosomiasis and Fluorescence Studies of Selected Diamidines, Jennifer Crystal Brown Barber
Rational Drug Design for Neglected Diseases: Implementation of Computational Methods to Construct Predictive Devices and Examine Mechanisms, Catharine Jane Collar
Roles of Serine 101, Histidine 310 and Valine 464 in the Reaction Catalyzed by Choline Oxidase from Arthrobacter Globiformis, Steffan Finnegan
Design and Synthesis of Novel Serotonin Receptor Ligands, Jeffrey D. Klenc
Design, Synthesis and Mechanistic Studies of Small Molecule Inhibitors of the Hypoxia Inducible Factor Pathway, Suazette Reid Mooring
Sequence-Specific and Conformation-Specific Targeting of Duplex and Quadruplex DNA Grooves with Small Molecules, Rupesh K. Nanjunda
Application of Boronic Acids in Medicinal Chemistry (Inhibitors, Sensors), Nanting Ni
Bead Modeling of Transport Properties of Macromolecules in Free Solution and in a Gel, Hongxia Pei
On the Catalytic Roles of HIS351, ASN510, and HIS466 in Choline Oxidase and the Kinetic Mechanism of Pyranose 2-Oxidase, Kunchala Rungsrisuriyachai
Development of RNA Microchip for the Detection of Pathogens, Sarah M. Spencer
Theses/Dissertations from 2009
Diagnosis and Inhibition Tools in Medicinal Chemistry, Senol Akay
Synthesis and Enzymatic Studies of Selenium Derivatized Nucleosides, Nucleotides and Nucleic Acids, Julianne Marie Caton-Williams
Metal-Assisted Hydrolysis of Biological Molecules, Sarah Shealy Cepeda
Development of Boronic Acid-Based Chemosensors, Shan Jin
Detection and Quantification of Organophosphate Pesticides in Human Serum, Peter Kuklenyik
On the Preorganization of the Active Site of Choline Oxidase for Hydride Transfer and Tunneling Mechanism, Osbourne Quaye
Synthesis, Structure and Function Studies of Selenium and Tellurium Derivatized Nucleic Acids, Jia Sheng
Design and Synthesis of Boronic Acid-Modified Nucleotides for Fluorescent Sensing and Cell Imaging, Xiaochuan Yang
Theses/Dissertations from 2008
Synthesis of Anthraquinone Derivatives and their Conjugates with 2'-Deoxynucleosides as New Probes for Electron Transfer Studies in DNA, Reham A. I. Abou-Elkhair
Application of Computer-Aided Drug Discovery Methodologies Towards the Rational Design of Drugs Against Infectious Diseases, Prashanth Athri
The Design and Evaluation of Boronic Acid Derivatives for the Recognition of Cell Surface Carbohydrates for Medicinal Applications, Sandra Navonne Craig
Rational Design of Calcium Biosensors, April L. Ellis
Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition, Lisa Michelle Jones
Bioanalytical Applications of Intramolecular H-Complexes of Near Infrared Bis(Heptamethine Cyanine) Dyes, JUNSEOK KIM
Determining The Site Specific Metal Binding and Structural Properties of EF-Hand Protein Using Grafting Approach, Hsiau-Wei Lee
Structure and Energetics of RNA - Protein Interactions for HIV RREIIB Targeting Zinc Finger Proteins., Subrata H. Mishra
Binding, Bending and G Jumping in the Minor Groove: Experimental and Theoretical Approaches, Maryam Rahimian
Application of Term-Rewriting Grammar in Chemical Reaction Prediction, Patra Volarath
Binding Studies of Near Infrared Cyanine Dyes with Human Serum Albumin and Poly-L-Lysine Using Optical Spectroscopy Methods, Amy Dawn Watson
Theses/Dissertations from 2007
The Extent of Perturbation of Skin Models by Transdermal Penetration Enhancers Investigated by 31P NMR and Fluorescence Spectroscopy, Charmita Patricia Burch
Zr(IV)-Assisted Peptide Hydrolysis, MIKI KASSAI
Capillary Electrochromatography-Mass Spectrometry (CEC-MS) of Surfactants, Dean Stephen Norton
Electrokinetic Modeling of Free Solution Electrophoresis, Yao Xin
Exploring the Role of Calcium Ions in Biological Systems by Computational Prediction and Protein Engineering, Yubin Zhou
Theses/Dissertations from 2006
Epoxidation of Alkenes by Dimethyldioxirane: Kinetics, Activation Parameters and Solvent Studies, Brian Shelton Crow
On the Mechanistic Roles of the Protein Positive Charge Close to the N(1)Flavin Locus in Choline Oxidase, Mahmoud Ghanem
Insights into Sulfonated Phthalocyanines; Insights into Anionic Tetraaryl Porphyrins; Irradiation of Cationic Metalloporphyrins Bound to DNA, Anila Fiaz Gill
Synthesis of Boronic Acid Based Sensors for Glucose and Sialic Acid and Synthesis of Novel and Selective PDE4 Enzyme Inhibitors, Gurpreet Kaur
Shape-Dependent Molecular Recognition of Specific Sequences of DNA by Heterocyclic Cations, Yi Miao
Design of Novel Molecular Micelles for Capillary Electrophoresis, Syed Asad Ali Rizvi
Crystallographic Analysis and Kinetic Studies of HIV-1 Protease and Drug-Resistant Mutants, Yunfeng Tie
Selective Recognition of Quadruplex DNA by Small Molecules, Elizabeth W. White
Syntheses and DNA Interactions of Acridine and Phenothiazine Based Photosensitizers, Beth Wilson