Date of Award
Master of Science (MS)
Cocatalyzed reactions using Brønsted acids and chiral N-heterocyclic carbenes to yield highly enantioselective products have been reported recently in many journals. The development of new chiral N-heterocyclic carbenes is a competitive field among synthetic chemist. In a recent study we found that conjugated trienes could be cyclized using Brønsted acids and chiral N-heterocyclic carbenes. The synthesis of novel chiral N-heterocyclic carbene precursors, and the precursors to novel conjugated trienes are reported herein.
Wilkerson, Phillip D., "Synthesis of Chiral N-Heterocyclic Carbene Precursors and Key Intermediates for Catalytic Enantioselective Cyclizations of Conjugated Trienes" (2012). Chemistry Theses. Paper 49.